Cat-App: category approaches and ‘read-across’ in regulatory programmes
A new approach to evaluating the toxicological effects of petroleum substances by making use of existing test data aims to reduce, and eventually eliminate, the use of animals for toxicity testing.
A chemical–biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives
Comparative assessment of potential human health impacts is a critical step in evaluating both chemical alternatives and existing products on the market. Most alternatives assessments are conducted on a chemical-by-chemical basis and it is seldom acknowledged that humans are exposed to complex products, not individual substances.
IN PRESS: Grouping of UVCB substances for chemical composition-based read-across using ion mobility mass spectrometry
Grimm FA, Russell WK, Luo Y-S, Iwata Y, Chiu WA, Roy T, Boogaard PJ, Ketelslegers HB, Rusyn I. Grouping of UVCB substances for chemical composition-based read-across using ion mobility mass spectrometry. Env Sci Technol (in press)