The carcinogenicity and developmental toxicity of unrefined mineral oil is related to its 3–7 ring polycyclic aromatic compounds (PAC) content. Therefore, refining operations focus on the targeted removal PAC from mineral oil that may contain aromatics of low...
Are dose–response relationships for benzene and health effects such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) supra-linear, with disproportionately high risks at low concentrations, e.g. below 1 ppm? To investigate this hypothesis, we apply...
The thyroid gland, and its associated endocrine hormones, is a growing area of interest in regulatory toxicology due to its important role in metabolism, growth and development. This report presents a review of the toxicology data on chemically complex petroleum...
Report no. 6/16: The IP 346 method was adopted as a screening assay to predict the carcinogenicity of specific petroleum streams. Its application is based on a strong correlation with results from over 100 mouse dermal carcinogenicity studies, which were reported in a...
Report no. 4/16: This report focuses on published toxicology and epidemiology studies that have examined the relationship between sulphur dioxide exposures and the occurrence of acute and chronic health effects in laboratory animals and humans. All relevant studies...
