Understanding the reproductive toxicity of gas oil substances: new Repro 1B self-classification and updated risk assessment

Concawe Review 33.2 Special REACH Edition - Article 2

This article synthesises the scientific findings and REACH dossier developments concerning a reproductive and developmental toxicity assessment of 14 substances across three gas oil categories, focusing primarily on the OECD Test Guideline 422 results generated as part of the ongoing human health testing strategy of Concawe substances. Emphasis is placed on the implications of the newly determined self-classification as Reproductive Toxicity Category 1B (H360FD) for all gas oils, indicative of adverse effects on fertility and developmental outcomes. Further impacts were evaluated, triggering a review of exposure scenarios and risk management practices alongside further scientific inquiries and research directions.