“New Technologies to Underpin Category Approaches and Read-across in Regulatory Programmes”

Cat-App was initiated with the aim to minimize the need for testing in vertebrate animals under regulatory programmes. This is achieved by grouping petroleum substances (PS) to make most optimal use of the toxicological information on PS by read-across of the available data within and (where needed and justified) between these groups. A framework will be developed for grouping based on chemical-biological properties combining multiple streams of information comprising PS production type/refining process, physical-chemical properties, chemical analytical profiles, existing (eco-) toxicological data and a comprehensive array of biological responses in a broad spectrum of in vitro systems.